基因名：
JAK3
产品别名：
JAK-3； JAK3_HUMAN； JAKL； L-JAK； LJAK； JAK3； Janus kinase 3； Janus kinase 3； tyrosine-protein kinase JAK3； Janus kinase 3 (a protein tyrosine kinase, leukocyte)； leukocyte Janus kinase； Janus激酶3(JAK3)； 磷酸化蛋白酪氨酸激酶JAK-3； 蛋白酪氨酸激酶JAK-3；
背景信息：
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
