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重组组蛋白去甲基化酶JARID2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant JARID2
Recombinant jumonji and AT-rich interaction domain containing 2 protein
基因名:

JARID2


产品别名:

JMJ; JARID2; jumonji and AT-rich interaction domain containing 2; jumonji and AT-rich interaction domain containing 2; protein Jumonji; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji-like protein; jumonji/ARID domain-containing protein 2; 组蛋白去甲基化酶JARID2;


背景信息:
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
 
 
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