基因名:
JUNB
产品别名:
AP-1; JUNB; JunB proto-oncogene, AP-1 transcription factor subunit; JunB proto-oncogene, AP-1 transcription factor subunit; transcription factor JunB; activator protein 1; jun B proto-oncogene; transcription factor AP-1 subunit JunB; transcription factor jun-B; Jun B原癌基因(JUNB); 活化蛋白激酶B; 磷酸化活化蛋白激酶B;
背景信息:
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.