基因名:
KCNJ6
产品别名:
BIR1; GIRK-2; GIRK2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; hiGIRK2; KCNJ6; potassium inwardly rectifying channel subfamily J member 6; potassium inwardly rectifying channel subfamily J member 6; G protein-activated inward rectifier potassium channel 2; inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; potassium channel, inwardly rectifying subfamily J, member 6; potassium voltage-gated channel subfamily J member 6; G蛋白激活内流钾通道蛋白2;
背景信息:
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.