基因名:
KEL
产品别名:
CD238; ECE3; Kell; KEL; Kell metallo-endopeptidase (Kell blood group); Kell metallo-endopeptidase (Kell blood group); kell blood group glycoprotein; Kell blood group, metallo-endopeptidase; Kell glycoprotein; Kell血型糖蛋白(KEL); 凯尔血型糖蛋白CD238;
背景信息:
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.