基因名：
KLK1
产品别名：
KLKR； Klk6； hK1； KLK1； kallikrein 1； kallikrein 1； kallikrein-1； glandular kallikrein 1； kallikrein 1, renal/pancreas/salivary； kallikrein serine protease 1； kidney/pancreas/salivary gland kallikrein； tissue kallikrein； 激肽释放酶1； 激肽释放酶1(KLK1)；
背景信息：
Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
