基因名：
KLRC1
产品别名：
CD159A； NKG2； NKG2A； KLRC1； killer cell lectin like receptor C1； killer cell lectin like receptor C1； NKG2-A/NKG2-B type II integral membrane protein； C-lectin type II protein； CD159 antigen-like family member A； NK cell receptor A； NKG2-1/B activating NK receptor； NKG2-A/B type II integral membrane protein； NKG2-A/B-activating NK receptor； killer cell lectin-like receptor subfamily C, member 1； natural killer cell lectin； natural killer group protein 2； NKG2A/CD159a蛋白； NK细胞受体2A；
背景信息：
NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens.
