基因名:
KPNA4
产品别名:
IPOA3; QIP1; SRP3; KPNA4; karyopherin subunit alpha 4; karyopherin subunit alpha 4; importin subunit alpha-3; importin alpha Q1; importin subunit alpha-4; karyopherin alpha 4 (importin alpha 3); KPNA4蛋白; 亲核素α4(KPNa4);
背景信息:
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]