基因名：
TNPO1
产品别名：
IPO2； KPNB2； MIP； MIP1； TRN； TNPO1； transportin 1； transportin 1； transportin-1； M9 region interaction protein； importin 2； importin beta 2； karyopherin (importin) beta 2； karyopherin beta-2； 转运蛋白1； 转运蛋白1(TNPO1)；
背景信息：
Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.
