基因名:
KRT19
产品别名:
CK19; K19; K1CS; KRT19; keratin 19; keratin 19; keratin, type I cytoskeletal 19; 40-kDa keratin intermediate filament; CK-19; cytokeratin 19; keratin 19, type I; keratin, type I, 40-kd; 细胞角蛋白19; 细胞角蛋白19片段(CYFR21-1); 细胞角蛋白19,17,14,42,10; 角蛋白19(CK19); 角蛋白19(CK19)真核蛋白;
背景信息:
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.