基因名：
STMN1
产品别名：
C1orf215； LAP18； Lag； OP18； PP17； PP19； PR22； SMN； STMN1； stathmin 1； stathmin 1； stathmin； leukemia-associated phosphoprotein p18； metablastin； oncoprotein 18； phosphoprotein 19； phosphoprotein p19； prosolin； stathmin 1/oncoprotein 18； testicular tissue protein Li 189； transmembrane protein C1orf215； 白血病相关蛋白18/癌蛋白18； 磷酸化原癌基因蛋白18； 胞浆磷蛋白1(STMN1)；
背景信息：
Stathmin (STMN1) is a ubiquitous cytosolic phosphoprotein which belongs to the Stathmin family. STMN1 is expressed in many tissues, with the highest expression in the brain, spinal cord, and cerebellum. It can also be expressed in the colon, ovary, placenta, uterus, and trachea. STMN1 participates in the regulation of the microtubule filament structure by destabilizing microtubules. STMN1 promotes the disassembly of microtubules and prevents assembly. STMN1 is involved in the control of the learned and innate fear. STMN1 is an intracellular relay integrating regulatory signals of the cellular environment and as an Oncoprotein in regulation of the cell cycle. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Mutation in STMN1 effects cell homeostasis that may lead to tumorigenicity.
