基因名:
LMO2
产品别名:
LMO-2; RBTN2; RBTNL1; RHOM2; TTG2; LMO2; LIM domain only 2; LIM domain only 2; rhombotin-2; LIM domain only protein 2; T-cell translocation gene 2; T-cell translocation protein 2; cysteine-rich protein TTG-2; rhombotin-like 1; T淋巴细胞易位蛋白2; 斜方蛋白样蛋白1(RHOM2);
背景信息:
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]