基因名:
LNPEP
产品别名:
CAP; IRAP; P-LAP; PLAP; LNPEP; leucyl and cystinyl aminopeptidase; leucyl and cystinyl aminopeptidase; leucyl-cystinyl aminopeptidase; AT (4) receptor; angiotensin IV receptor; cystinyl aminopeptidase; insulin-regulated aminopeptidase; insulin-regulated membrane aminopeptidase; insulin-responsive aminopeptidase; otase; oxytocinase; placental leucine aminopeptidase; vasopressinase; 亮氨酰/半胱氨酰氨肽酶(LNPEP); 胰岛素调节膜氨基肽酶;
背景信息:
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]