基因名:
LPL
产品别名:
HDLCQ11; LIPD; LPL; lipoprotein lipase; lipoprotein lipase; lipoprotein lipase; phospholipase A1; 脂蛋白脂酶; 脂蛋白脂酶(LPL);
背景信息:
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]