基因名：
LTBP1
产品别名：
ARCL2E； LTBP1； latent transforming growth factor beta binding protein 1； latent transforming growth factor beta binding protein 1； latent-transforming growth factor beta-binding protein 1； LTBP-1； TGF-beta1-BP-1； transforming growth factor beta-1-binding protein 1； 组织内转化生长因子β结合蛋白1(LTBP1)； 转化生长因子β1结合蛋白1；
背景信息：
Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas.
