基因名:
LYN
产品别名:
JTK8; p53Lyn; p56Lyn; LYN; LYN proto-oncogene, Src family tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; tyrosine-protein kinase Lyn; lck/Yes-related novel protein tyrosine kinase; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; V-Yes-1 Yamaguchi肉瘤病毒相关癌基因同源物(LYN); 磷酸化膜相关蛋白酪氨酸激酶Lyn; 膜相关蛋白酪氨酸激酶Lyn;
背景信息:
LYN contains one protein kinase domain, one SH2 domain, one SH3 domain, and the protein kinase domain plays an important role in its localization in the cell membrane. LYN is also thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. In addition, LYN is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).