基因名：
MARK1
产品别名：
MARK； Par-1c； Par1c； MARK1； microtubule affinity regulating kinase 1； microtubule affinity regulating kinase 1； serine/threonine-protein kinase MARK1； MAP/microtubule affinity-regulating kinase 1； PAR1 homolog c； 丝氨酸/苏氨酸蛋白激酶MARK1； 磷酸化丝氨酸/苏氨酸蛋白激酶MARK1；
背景信息：
MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
