基因名:
MAT1A
产品别名:
MAT; MATA1; SAMS; SAMS1; MAT1A; methionine adenosyltransferase 1A; methionine adenosyltransferase 1A; S-adenosylmethionine synthase isoform type-1; MAT 1; MAT-I/III; adoMet synthase 1; adoMet synthetase 1; methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; methionine adenosyltransferase I/III; 腺苷蛋氨酸1; 蛋氨酸腺苷转移酶Ⅰα(MAT1a);
背景信息:
MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. Mutations in this gene are associated with methionine adenosyltransferase deficiency.