基因名:
MCC
产品别名:
MCC1; MCC; MCC regulator of WNT signaling pathway; MCC regulator of WNT signaling pathway; colorectal mutant cancer protein; MCC, WNT signaling pathway regulator; mutated in colorectal cancers; 大肠癌肿瘤突变蛋白;
背景信息:
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].