重组Bcl2相关髓细胞白血病序列1(MCL1)蛋白

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重组磷酸化髓样细胞白血病-1蛋白
Recombinant MCL1

基因名：

MCL1

产品别名：

BCL2L3； EAT； MCL1-ES； MCL1L； MCL1S； Mcl-1； TM； bcl2-L-3； mcl1/EAT； MCL1； MCL1 apoptosis regulator, BCL2 family member； MCL1 apoptosis regulator, BCL2 family member； induced myeloid leukemia cell differentiation protein Mcl-1； BCL2 family apoptosis regulator； MCL1, BCL2 family apoptosis regulator； bcl-2-like protein 3； bcl-2-related protein EAT/mcl1； myeloid cell leukemia 1； myeloid cell leukemia ES； myeloid cell leukemia sequence 1 (BCL2-related)； Bcl2相关髓细胞白血病序列1(MCL1)；磷酸化髓样细胞白血病-1；磷酸化髓样细胞白血病1；髓样细胞白血病-1；

背景信息：

Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。