基因名：
ME2
产品别名：
ODS1； ME2； malic enzyme 2； malic enzyme 2； NAD-dependent malic enzyme, mitochondrial； NAD-ME； malate dehydrogenase (oxaloacetate-decarboxylating)； malic enzyme 2, NAD(+)-dependent, mitochondrial； pyruvic-malic carboxylase； NADP依赖性苹果酶2(ME2)； 胞浆苹果酸酶2；
背景信息：
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
