基因名:
MEF2D
产品别名:
MEF2D; myocyte enhancer factor 2D; myocyte enhancer factor 2D; myocyte-specific enhancer factor 2D; MADS box transcription enhancer factor 2, polypeptide D; 磷酸化肌细胞特异性增强因子2D; 肌细胞特异性增强因子2D;
背景信息:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.