基因名：
MEIS1
产品别名：
MEIS1； Meis homeobox 1； Meis homeobox 1； homeobox protein Meis1； Meis1, myeloid ecotropic viral integration site 1 homolog； WUGSC:H_NH0444B04.1； leukemogenic homolog protein； 同源盒蛋白Meis1；
背景信息：
Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Tissue specificity; Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.
