基因名：
AFDN
产品别名：
AF6； MLL-AF6； MLLT4； l-afadin； AFDN； afadin, adherens junction formation factor； afadin, adherens junction formation factor； afadin； ALL1-fused gene from chromosome 6 protein； myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4； myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4； protein AF-6； 丝状肌动蛋白结合蛋白； 磷酸化丝状肌动蛋白结合蛋白；
背景信息：
This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
