基因名：
FOXO4
产品别名：
AFX； AFX1； MLLT7； FOXO4； forkhead box O4； forkhead box O4； forkhead box protein O4； fork head domain transcription factor AFX1； myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7； 叉头蛋白O4； 磷酸化叉头蛋白4；
背景信息：
FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
