基因名：
MMP3
产品别名：
CHDS6； MMP-3； SL-1； STMY； STMY1； STR1； MMP3； matrix metallopeptidase 3； matrix metallopeptidase 3； stromelysin-1； matrix metalloproteinase 3 (stromelysin 1, progelatinase)； proteoglycanase； transin-1； MMP-3蛋白； 基质金属蛋白酶3； 基质金属蛋白酶3(MMP3)； 基质金属蛋白酶3(MMP3)真核蛋白； 基质金属蛋白酶3蛋白；
背景信息：
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
