基因名:
MTTP
产品别名:
ABL; MTP; MTTP; microsomal triglyceride transfer protein; microsomal triglyceride transfer protein; microsomal triglyceride transfer protein large subunit; microsomal triglyceride transfer protein (large polypeptide, 88kDa); 微粒体甘油三酯转运蛋白; 微粒体甘油三酸酯转运蛋白(MTTP);
背景信息:
MTTP catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. MTTP is required for the secretion of plasma lipoproteins that contain apolipoprotein B. It is positively regulated by cholesterol and negatively regulated by insulin. Defects in MTP are the cause of abetalipoproteinemia.