基因名:
MYL3
产品别名:
CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl; MYL3; myosin light chain 3; myosin light chain 3; myosin light chain 3; CMLC1; cardiac myosin light chain 1; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; ventricular myosin alkali light chain; ventricular myosin light chain 1; ventricular/slow twitch myosin alkali light chain; 肌球蛋白轻链3; 肌球蛋白轻链3(MYL3);
背景信息:
Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each 200,000 daltons, and four light chains each 16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. Human myosin light chain has clinical application as a cardiac marker.