基因名:
NCF4
产品别名:
CGD3; NCF; P40PHOX; SH3PXD4; NCF4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4; neutrophil cytosol factor 4; NCF-4; SH3 and PX domain-containing protein 4; neutrophil NADPH oxidase factor 4; neutrophil cytosolic factor 4, 40kDa; p40-phox; 嗜中性粒细胞胞浆因子4; 嗜中性粒细胞胞浆因子4(NCF4); 磷酸化嗜中性粒细胞胞浆因子4;
背景信息:
NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.