基因名:
NFATC2
产品别名:
NFAT1; NFATP; NFATC2; nuclear factor of activated T cells 2; nuclear factor of activated T cells 2; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; T cell transcription factor NFAT1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; preexisting nuclear factor of activated T-cells 2; 核因子活化T细胞胞浆蛋白2; 活化T-细胞核因子2(NFATC2); 磷酸化核因子活化T细胞胞浆蛋白2;
背景信息:
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]