基因名:
NFE2L2
产品别名:
HEBP1; IMDDHH; NRF2; Nrf-2; NFE2L2; NFE2 like bZIP transcription factor 2; NFE2 like bZIP transcription factor 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; 核因子2相关因子2; 磷酸化核因子2相关因子2(Ser40); 红细胞衍生核因子2样蛋白2(NFE2L2);
背景信息:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.