基因名:
NFKBIB
产品别名:
IKBB; TRIP9; NFKBIB; NFKB inhibitor beta; NFKB inhibitor beta; NF-kappa-B inhibitor beta; I-kappa-B-beta; NF-kappa-BIB; TR-interacting protein 9; TRIP-9; ikB-B; ikB-beta; ikappaBbeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; thyroid receptor-interacting protein 9; NF-kappa-B抑制子beta; 核因子κB抑制因子β(IkBb); 磷酸化KB抑制蛋白β;
背景信息:
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].