基因名：
NFYA
产品别名：
CBF-A； CBF-B； HAP2； NF-YA； NFYA； nuclear transcription factor Y subunit alpha； nuclear transcription factor Y subunit alpha； nuclear transcription factor Y subunit alpha； CAAT-box DNA binding protein subunit A； CCAAT-binding transcription factor subunit B； HAP2 CCAAT-binding protein； Transcription factor NF-Y, A subunit； nuclear transcription factor Y subunit A； nuclear transcription factor Y, alpha； 核转录因子YA；
背景信息：
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]
