基因名：
NME1
产品别名：
AWD； GAAD； NB； NBS； NDKA； NDPK-A； NDPKA； NM23； NM23-H1； NME1； NME/NM23 nucleoside diphosphate kinase 1； NME/NM23 nucleoside diphosphate kinase 1； nucleoside diphosphate kinase A； NDP kinase A； epididymis secretory sperm binding protein； granzyme A-activated DNase； metastasis inhibition factor nm23； non-metastatic cells 1, protein (NM23A) expressed in； tumor metastatic process-associated protein； 肿瘤抑制基因； 非转移细胞1表达NM23A蛋白(NME1)；
背景信息：
Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
