基因名:
NPPB
产品别名:
BNP; Iso-ANP; NPPB; natriuretic peptide B; natriuretic peptide B; natriuretic peptides B; brain natriuretic factor prohormone; brain type natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic protein; preproBNP; proBNP; 白细胞介素10蛋白; 脑纳素前体; 脑钠素(BNP); 脑钠素(BNP)合成多肽; 脑钠素/利钠肽; 脑钠素/利钠肽蛋白; 脑钠肽前体蛋白;
背景信息:
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such as atrial fibrillation (AF) and atrial septal defect in patients without HF.