基因名：
NPR3
产品别名：
ANP-C； ANPR-C； ANPRC； BOMOS； C5orf23； GUCY2B； NPR-C； NPRC； NPR3； natriuretic peptide receptor 3； natriuretic peptide receptor 3； atrial natriuretic peptide receptor 3； atrial natriuretic peptide clearance receptor； atrial natriuretic peptide receptor type C； atrionatriuretic peptide receptor C； guanylate cyclase C； natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)； 利钠肽受体C； 钠尿肽受体3(NPR3)；
背景信息：
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation.
