基因名：
NUCB2
产品别名：
HEL-S-109； NEFA； NUCB2； nucleobindin 2； nucleobindin 2； nucleobindin-2； DNA-binding protein NEFA； epididymis secretory protein Li 109； gastric cancer antigen Zg4； nesfatin 1； novel DNA binding/EF-hand/leucine zipper protein； nucleobinding 2； prepronesfatin； 新的饱食分子蛋白； 核连蛋白2(NUCB2)；
背景信息：
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
