基因名：
OAS2
产品别名：
OAS2； 2'-5'-oligoadenylate synthetase 2； 2'-5'-oligoadenylate synthetase 2； 2'-5'-oligoadenylate synthase 2； (2'-5')oligo(A) synthetase 2； 2'-5'-oligoadenylate synthetase 2, 69/71kDa； 2-5A synthase 2； p69 OAS / p71 OAS； 2',5'-寡腺苷酸合成酶2(OAS2)； 2'-5'-寡腺苷酸合成酶2；
背景信息：
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
