基因名:
PAK1
产品别名:
IDDMSSD; PAKalpha; alpha-PAK; p65-PAK; PAK1; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 1; serine/threonine-protein kinase PAK 1; STE20 homolog, yeast; p21 protein (Cdc42/Rac)-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21激活激酶1; p21蛋白激活激酶1(PAK1); 磷酸化p21激活激酶1; 磷酸化p21激活激酶1/2; 磷酸化p21激活激酶1/2/3; 磷酸化p21激活激酶1/3;
背景信息:
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]