基因名:
PAPPA
产品别名:
ASBABP2; DIPLA1; IGFBP-4ase; PAPA; PAPP-A; PAPPA1; PAPPA; pappalysin 1; pappalysin 1; pappalysin-1; IGF-dependent IGFBP-4 protease; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; insulin-like growth factor-dependent IGF binding protein-4 protease; pregnancy-associated plasma protein A, pappalysin 1; 妊娠关联血浆蛋白A(PAPPA); 妊娠相关血浆蛋白A;
背景信息:
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.