基因名:
PAX7
产品别名:
HUP1; MYOSCO; PAX7B; RMS2; PAX7; paired box 7; paired box 7; paired box protein Pax-7; PAX7 transcriptional factor; paired box homeotic gene 7; paired domain gene 7; 配对盒基因7;
背景信息:
PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of PAX7 is unknown but it is speculated to be involved in tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.