基因名：
PCK2
产品别名：
PEPCK； PEPCK-M； PEPCK2； PCK2； phosphoenolpyruvate carboxykinase 2, mitochondrial； phosphoenolpyruvate carboxykinase 2, mitochondrial； phosphoenolpyruvate carboxykinase [GTP], mitochondrial； PEP carboxykinase； epididymis secretory sperm binding protein； phosphopyruvate carboxylase； 磷酸烯醇式丙酮酸羧激酶2(PCK2)； 磷酸羧化酶2；
背景信息：
PCK2 is a a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.
