基因名:
PEPD
产品别名:
PROLIDASE; PEPD; peptidase D; peptidase D; xaa-Pro dipeptidase; X-Pro dipeptidase; aminoacyl-L-proline hydrolase; imidodipeptidase; proline dipeptidase; testicular tissue protein Li 138; 肽酶D(PEPD); 脯氨酸二肽酶;
背景信息:
PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in collagen metabolism because of the high levels of imino acids. Defects in PEPD are a cause of prolidase deficiency which is an autosomal recessive disorder associated with iminodipeptiduria.