基因名:
PFDN5
产品别名:
MM-1; MM1; PFD5; PFDN5; prefoldin subunit 5; prefoldin subunit 5; prefoldin subunit 5; c-myc binding protein; myc modulator-1; 前折叠蛋白亚基5; 前折叠蛋白亚基5(PFDN5);
背景信息:
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]