基因名：
PI3
产品别名：
ESI； SKALP； WAP3； WFDC14； cementoin； PI3； peptidase inhibitor 3； peptidase inhibitor 3； elafin； PI-3； WAP four-disulfide core domain 14； WAP four-disulfide core domain protein 14； elastase-specific inhibitor； peptidase inhibitor 3, skin-derived； pre-elafin； protease inhibitor 3, skin-derived (SKALP)； protease inhibitor WAP3； skin-derived antileukoproteinase； trappin-2； 弹性蛋白酶抑制剂； 皮肤衍生肽酶抑制因子3(PI3)；
背景信息：
Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.
