重组红细胞磷脂酰肌醇聚糖A蛋白

首页蛋白库基因库产品会员服务

位置：首页 > 产品库 > 重组红细胞磷脂酰肌醇聚糖A蛋白

立即咨询

重组红细胞磷脂酰肌醇聚糖A蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant PIGA
Recombinant phosphatidylinositol glycan anchor biosynthesis class A protein

基因名：

PIGA

产品别名：

GPI3； MCAHS2； NEDEPH； PIG-A； PNH1； PIGA； phosphatidylinositol glycan anchor biosynthesis class A； phosphatidylinositol glycan anchor biosynthesis class A； phosphatidylinositol N-acetylglucosaminyltransferase subunit A； GLCNAC-PI synthesis protein； GPI anchor biosynthesis； class A GlcNAc-inositol phospholipid assembly protein； phosphatidylinositol-glycan biosynthesis, class A protein；红细胞磷脂酰肌醇聚糖A；

背景信息：

PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure.