基因名:
PITX3
产品别名:
ASGD1; ASMD; ASOD; CTPP4; CTRCT11; PTX3; PITX3; paired like homeodomain 3; paired like homeodomain 3; pituitary homeobox 3; homeobox protein PITX3;
背景信息:
The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement; mutations of the PITX3 gene have been associated with a familial form of cataracts.