基因名：
PKLR
产品别名：
PK1； PKL； PKRL； RPK； PKLR； pyruvate kinase L/R； pyruvate kinase L/R； pyruvate kinase PKLR； R-type/L-type pyruvate kinase； pyruvate kinase 1； pyruvate kinase isozyme R/L； pyruvate kinase isozymes L/R； pyruvate kinase isozymes R/L； pyruvate kinase type L； pyruvate kinase, liver and RBC； pyruvate kinase, liver and blood cell； red cell/liver pyruvate kinase； 丙酮酸激酶同工酶R/L(PKLR)； 丙酮酸激酶肝型；
背景信息：
Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver; R is found in red cells; M1 is the main form in muscle, heart and brain; M2 is found in early fetal tissues. PKLR exists as a homotetramer and catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in PKLR are also the cause of pyruvate kinase deficiency of red cells, which is a frequent cause of hereditary non-spherocytic hemolytic anemia.
