基因名:
PLAG1
产品别名:
PSA; SGPA; SRS4; ZNF912; PLAG1; PLAG1 zinc finger; PLAG1 zinc finger; zinc finger protein PLAG1; COL1A2/PLAG1 fusion; HAS2/PLAG1 fusion; pleiomorphic adenoma gene 1; 多型性腺瘤基因1蛋白;
背景信息:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]