基因名:
PLCL1
产品别名:
PLCE; PLCL; PLDL1; PPP1R127; PRIP; PLCL1; phospholipase C like 1 (inactive); phospholipase C like 1 (inactive); inactive phospholipase C-like protein 1; PLC-L1; phospholipase C, epsilon; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; protein phosphatase 1, regulatory subunit 127; 磷脂酶C1样蛋白; 磷酯酶C样蛋白1(PLCL1);
背景信息:
PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.